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Nitric Oxide: Modulator of Cell-Cell Interactions in the Microcirculation

Edited by Paul Kubes






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This book outlines the potential role of nitric oxide in the physiology and pathophysiology of the microcirculation with special emphasis on leukocyte-endothelial cell interactions. The chemistry of nitric oxide as it pertains to the vasculature is summarized. Among other aspects, the very controversial area of nitric oxide and ischemia/reperfusion is dealt with, followed by a chapter on a new therapeutic approach to using nitric oxide in the leukocyte-dependent ulceration associated with non-steroidal anti-inflammatory drugs. This chapter summarizes data on the development of a novel series of non-steroidal anti-inflammatory drugs modified to incorporate a nitric oxide-releasing moiety with reduced gastrointestinal toxicity. This is the most up-to-date book on the role of nitric oxide and leukocyte/platelet biology.

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Normally shipped | Enquiries only
Publisher | Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Published date | 13 Sep 1995
Language |
Format | Hardback
Pages | 171
Dimensions | 260 x 0 x 0mm (L x W x H)
Weight | 670g
ISBN | 978-3-5406-0036-7
Readership Age |
BISAC | medical / anesthesiology


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