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Centromeres and Kinetochores: Discovering the Molecular Mechanisms Underlying Chromosome Inheritance

Edited by Ben E. Black

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normal price: R 10 306.95

Price: R 9 790.95


| book description |

This book presents the latest advances concerning the regulation of chromosome segregation during cell division by means of centromeres and kinetochores. The authors cover both state-of-the-art techniques and a range of species and model systems, shedding new light on the molecular mechanisms controlling the transmission of genetic material between cell divisions and from parent to offspring.  The chapters cover five major areas related to the current study of centromeres and kinetochores: 1) their genetic and epigenetic features, 2) key breakthroughs at the molecular, proteomic, imaging and biochemical level, 3) the constitutive centromere proteins, 4) the role of centromere proteins in the physical process of chromosome segregation and its careful orchestration through elaborate regulation, and 5) intersections with reproductive biology, human health and disease, as well as chromosome evolution. The book offers an informative and provocative guide for newcomers as wellas those already acquainted with the field.

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Normally shipped | Usually dispatched in 3 to 4 weeks as supplier is out of stock
Publisher | Springer International Publishing AG
Published date | 10 Aug 2018
Language |
Format | Paperback / softback
Pages | 554
Dimensions | 235 x 155 x 0mm (L x W x H)
Weight | 0g
ISBN | 978-3-3198-6436-5
Readership Age |
BISAC | science / life sciences / biology / general


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