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Nrf2 and its Modulation in Inflammation

Edited by Huai Deng

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normal price: R 4 600.95

Price: R 4 370.95

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Nrf2, a transcription factor that mediates transcriptional responses to oxidative and xenobiotic stresses, plays a central role in cellular protection against internal or external toxins. Defects in Nrf2 and the relevant regulatory pathways are associated with a number of pathologies including inflammation, respiratory diseases, cardiovascular dysfunctions, metabolic syndrome and diabetes, neurodegeneration, and cancer. This book comprehensively reviews the up-to-date discoveries for the roles of Nrf2 in several human diseases in the context of inflammation. In particular, the molecular mechanisms that mediate the functions of Nrf2 and its interacting network in inflammation and pathogenesis are explicated. In addition, the research and therapeutic applications of Nrf2-targeting compounds in different diseases were summarized. This book is expected to be a valuable reference for worldwide researchers conducting both mechanistic and therapeutic studies of Nrf2 and relevant factors. Â Â Â

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The Memory Collectors: A Novel

Dete Meserve
Paperback / softback
320 pages

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Survive the AI Apocalypse: A guide for solutionists

Bronwyn Williams
Paperback / softback
232 pages
was: R 340.95
now: R 306.95
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Look around you is anything real or normal any more? News, images and videos created by AI are everywhere.

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The Coming Wave: AI, Power and Our Future

Mustafa Suleyman
Paperback / softback
352 pages
was: R 295.95
now: R 265.95
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The Colonialist: The Vision of Cecil Rhodes

William Kelleher Storey
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528 pages
was: R 425.95
now: R 382.95
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This first comprehensive biography of Cecil Rhodes in a generation illuminates Rhodesâ€™s vision for the expansion of imperialism in southern Africa, connecting politics and industry to internal development, and examines how this fueled a lasting, white-dominated colonial society.

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