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books
| book details |
The Immunological Synapse - Part B: Volume 178
Volume editor Clément Thomas, Volume editor Lorenzo Galluzzi
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normal price: R 7 477.95
Price: R 6 729.95
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| book description |
The Immunological Synapse - Part B, Volume 178 in the Methods in Cell Biology series provides state-of-the-art methods for the study of the immunological synapse. This first volume covers various aspects on T cell and natural killer (NK) cell synapses, including imaging polarized granule release using TIRF microscopy, analysis of actin reorganization and centrosome polarization, redirected degranulation, live cell-imaging to quantify cytotoxic and chemotactic dynamics, quantification of interactions between APCs and T cells, assessment of membrane lipid state at the immunological synapse, proteomic analysis and imaging of NK-tumor cell interaction, evaluating natural killer cell effector functions against breast cancer cells derived from human tumor tissue, evaluation of chimeric antigen receptor (CAR)-modified cell immunological synapse quality using the glass-supported planar lipid bilayer, and monitoring potency of therapeutic CAR T cells. It also includes one chapter on quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers, and one chapter on the murine antibody-dependent cellular phagocytosis assay.
| product details |
Normally shipped |
Publisher | Elsevier Science Publishing Co Inc
Published date | 11 Jul 2023
Language |
Format | Hardback
Pages | 222
Dimensions | 235 x 191 x 0mm (L x W x H)
Weight | 630g
ISBN | 978-0-4431-9163-3
Readership Age |
BISAC | science / life sciences / biology / developmental biology
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