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Hematopoietic Stem Cell Transplantation

Edited by Anthony D. Ho, Edited by Rainer Haas, Edited by Richard E. Champlin

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normal price: R 2 861.95

Price: R 2 575.95


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This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life. Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation summarizes current understanding and development of clinical allogeneic HSC transplantation discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors details detection of bone marrow contamination by tumor cells and removal procedures focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors explores the effects of growth factor administration and leukapheresis on PB stem cell donors shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells employs automated fluorescence image cytometry to study early HSC behavior following seeding Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study,

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Normally shipped | This title will take longer to obtain, and should be delivered in 6-8 weeks
Publisher | Taylor & Francis Ltd
Published date | 1 Nov 2019
Language |
Format | Paperback / softback
Pages | 624
Dimensions | 246 x 174 x 0mm (L x W x H)
Weight | 1150g
ISBN | 978-0-3673-9831-6
Readership Age |
BISAC | medical / general


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Normally shipped | Usually dispatched in 3 to 4 weeks as supplier is out of stock
Readership Age |
Normal Price | R 3 383.95
Price | R 3 045.95 | on special |



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