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books
| book details |
Polymers and Nanomaterials for Gene Therapy
Edited by Ravin Narain
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| on special |
normal price: R 6 280.95
Price: R 5 966.95
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| book description |
Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy.
| product details |
Normally shipped |
Publisher | Elsevier Science & Technology
Published date | 19 Jan 2016
Language |
Format | Hardback
Pages | 302
Dimensions | 229 x 152 x 0mm (L x W x H)
Weight | 440g
ISBN | 978-0-0810-0520-0
Readership Age |
BISAC | medical / genetics
| other options |
Normally shipped |
Readership Age |
Normal Price | R 8 972.95
Price | R 8 523.95
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Mason Coile
Paperback / softback
224 pages
was: R 520.95
now: R 468.95
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A terrifying locked-room mystery set in a remote outpost on Mars.
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An epic love story with the pulse of a thriller that asks: what would you risk for a second chance at first love?
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